Searchable abstracts of presentations at key conferences in endocrinology

ea0050oc5.2 | Reproduction and Neuroendocrinology | SFEBES2017

Kisspeptin modulates resting brain activity to alter responses to negative stimuli in humans

Comninos Alexander , Demetriou Lysia , Wall Matt , Shah Amar , Clarke Sophie , Narayanaswamy Shakunthala , Nesbitt Alexander , Izzi-Engbeaya Chioma , Prague Julia , Abbara Ali , Ratnasabapathy Risheka , Yang Lisa , Salem Victoria , Nijher Monica , Jayasena Channa , Tanner Mark , Bassett Paul , Mehta Amrish , Rabiner Ilan , Bloom Stephen , Dhillo Waljit

Kisspeptin is a crucial activator of reproductive function, stimulating GnRH neurons in the hypothalamus. However, kisspeptin and its receptor are also expressed in other brain regions including the limbic system, which has key roles in emotional processing. Kisspeptin signalling in the limbic system modulates emotional and sexual brain processing during tasks, however the effects of kisspeptin on underlying resting brain activity have not yet been studied. This is vital for o...

ea0050oc5.2 | Reproduction and Neuroendocrinology | SFEBES2017

Kisspeptin modulates resting brain activity to alter responses to negative stimuli in humans

Comninos Alexander , Demetriou Lysia , Wall Matt , Shah Amar , Clarke Sophie , Narayanaswamy Shakunthala , Nesbitt Alexander , Izzi-Engbeaya Chioma , Prague Julia , Abbara Ali , Ratnasabapathy Risheka , Yang Lisa , Salem Victoria , Nijher Monica , Jayasena Channa , Tanner Mark , Bassett Paul , Mehta Amrish , Rabiner Ilan , Bloom Stephen , Dhillo Waljit

Kisspeptin is a crucial activator of reproductive function, stimulating GnRH neurons in the hypothalamus. However, kisspeptin and its receptor are also expressed in other brain regions including the limbic system, which has key roles in emotional processing. Kisspeptin signalling in the limbic system modulates emotional and sexual brain processing during tasks, however the effects of kisspeptin on underlying resting brain activity have not yet been studied. This is vital for o...